Filling an obvious gap in the scientific literature, this practice-oriented reference is the first to tie together the working knowledge of large
screening centers in the pharmaceutical and biotechnological field. It spans the entire fi eld of this emerging discipline, from compound
acquisition to collection optimization for specific purposes, to technology and quality control. In so doing, it applies two decades of expertise gathered by several large pharmaceutical companies to current and future challenges in high-throughput screening. With its treatment of libraries of small molecules as well as biobanks containing biomolecules, microorganisms and tissue samples, this reference is universally applicable for any molecular scientist involved in a large screening program.

A conductor is one of classical music's most recognisable but misunderstood figures, attracting so many questions:

'Surely orchestras can play perfectly well without you? '

'Do you really make any difference to the performance?'

'Are the musicians even watching you?'

The Silent Musician is not a manual for conductors, nor a history of conducting. It is for all who wonder what conductors actually do, and why they matter.

The conductor--tuxedoed, imposingly poised above an orchestra, baton waving dramatically--is a familiar figure even for those who never set foot in an orchestral hall. As a veritable icon for classical music, the conductor has also been subjected to some ungenerous caricatures, presented variously as unhinged gesticulator, indulged megalomaniac, or even outright impostor. Consider, for example: Bugs Bunny as Leopold Stokowski, dramatically smashing his baton and then breaking into erratic poses with a forbidding intensity in his eyes, or Mickey Mouse in Fantasia, unwittingly conjuring dangerous magic with carefree gestures he doesn't understand. As these cliches betray, there is an aura of mystery around what a conductor actually does, often coupled with disbelief that he or she really makes a difference to the performance we hear. The Silent Musician deepens our understanding of what conductors do and why they matter. Neither an instruction manual for conductors, nor a history of conducting, the book instead explores the role of the conductor in noiselessly shaping the music that we hear. Writing in a clever, insightful, and often evocative style, world-renowned conductor Mark Wigglesworth deftly explores the philosophical underpinnings of conducting--from the conductor's relationship with musicians and the music, to the public and personal responsibilities conductors face--and examines the subtler components of their silent art, which include precision, charisma, diplomacy, and passion. Ultimately, Wigglesworth shows how conductors--by simultaneously keeping time and allowing time to expand--manage to shape ensemble music into an immersive, transformative experience, without ever making a sound.